RESEARCH PAPER
Cognitive behavioral therapy improves adherence to antiretroviral therapy
in HIV-infected patients: a prospective randomized controlled trial from eastern India
Submission date: 2016-08-26
Final revision date: 2016-12-08
Acceptance date: 2016-12-11
Publication date: 2017-04-25
HIV & AIDS Review 2017;16(2):89-95
KEYWORDS
AIDSantiretroviral therapyadherence to ARTcognitive behavioral therapy in HIVBeck’s depression score
TOPICS
psychological aspects of HIV and AIDSsocio-medical aspects of HIV and AIDSeducational aspects of HIV and AIDS
ABSTRACT
We know that human immunodeficiency virus (HIV) is an important pandemic of modern generation causing large death toll worldwide. India is also no exception with 2.12 million people already affected by HIV. The only way to reduce morbidity and mortality due to HIV is antiretroviral therapy (ART). But a high degree of adherence is critical for the effectiveness of ART, and non-adherence is associated with an overall poor outcome in HIV patients. We conducted a randomized controlled prospective study to find out the factors responsible for non-adherence to ART and to assess the role of cognitive behavioral therapy (CBT) to improve adherence. In this study, 60 HIV/AIDS patients with non-adherence (< 95% adherence) were randomized into two groups consisting of 30 patients each, one group (intervention) was administered structured CBT and the other group (control) was put on standard therapy. Factors responsible for non-adherence were overconcern about side effects (33%), polarized thinking (27%), mind reading (27%), and magnification (20%). Mean adherence was 100% in the intervention arm vs. 97.5% in controls (p = 0.00), Beck’s depression score was reduced significantly in the intervention group (p = 0.00), but no significant difference was noted in CD4 count (p = 0.37). We strongly recommend inclusion of CBT in the routine management protocol for HIV/AIDS.
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| eISSN: | 1732-2707 |
| ISSN: | 1730-1270 |
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