RESEARCH PAPER
Male involvement in prevention of mother-to-child transmission of HIV, and its association with knowledge and residence in Ethiopia: a systematic review and meta-analysis
1
Wollo University, Ethiopia
Submission date: 2022-04-08
Final revision date: 2022-05-10
Acceptance date: 2022-05-10
Online publication date: 2024-10-05
Publication date: 2024-09-20
HIV & AIDS Review 2024;23(3):253-261
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Male involvement is crucial in preventing vertical transmission of human immunodeficiency virus (HIV) among pregnant and lactating women. Different studies were conducted on male involvement in prevention of mother-to-child transmission (PMTCT) of HIV, but there is inconsistency among the findings. Thus, the aim of this systematic review and meta-analysis was to determine the pooled prevalence of male involvement in PMTCT of HIV, and its association with knowledge and residence in Ethiopia.
Material and methods:
Searching of articles was carried out from March 10 to April 20, 2020. Quality of each article was assessed by Newcastle-Ottawa scale for observational studies. Data were analyzed using STATA/SE version 14. Heterogeneity among the reported prevalence was assessed by computing values for c2, I2, and p-values. Random effects-model was applied to estimate the pooled effect. To minimize random variations among primary studies, sub-group analysis and meta-regression analysis were performed. For assessing publication bias, Egger and Begg tests were applied.
Results:
Sixteen research articles were included for this systematic review and meta-analysis, with 6,670 sample size. The overall pooled prevalence of male involvement in PMTCT of HIV was 37.93% (95% CI: 29.41-46.45%) in Ethiopia. Having good knowledge on HIV (OR = 4.77; 95% CI: 3.30-6.82%) and urban dwellers (OR = 2.69; 95% CI: 2.11-3.44%) were associated factors with male involvement in PMTCT.
Conclusions:
The level of male involvement in PMTCT of HIV in Ethiopia is low. Male involvement is influenced by knowledge on HIV and urban residence. The government of Ethiopia should give concern for rural male population to enhance their involvement in the prevention of mother-to-child HIV transmission.
Male involvement is crucial in preventing vertical transmission of human immunodeficiency virus (HIV) among pregnant and lactating women. Different studies were conducted on male involvement in prevention of mother-to-child transmission (PMTCT) of HIV, but there is inconsistency among the findings. Thus, the aim of this systematic review and meta-analysis was to determine the pooled prevalence of male involvement in PMTCT of HIV, and its association with knowledge and residence in Ethiopia.
Material and methods:
Searching of articles was carried out from March 10 to April 20, 2020. Quality of each article was assessed by Newcastle-Ottawa scale for observational studies. Data were analyzed using STATA/SE version 14. Heterogeneity among the reported prevalence was assessed by computing values for c2, I2, and p-values. Random effects-model was applied to estimate the pooled effect. To minimize random variations among primary studies, sub-group analysis and meta-regression analysis were performed. For assessing publication bias, Egger and Begg tests were applied.
Results:
Sixteen research articles were included for this systematic review and meta-analysis, with 6,670 sample size. The overall pooled prevalence of male involvement in PMTCT of HIV was 37.93% (95% CI: 29.41-46.45%) in Ethiopia. Having good knowledge on HIV (OR = 4.77; 95% CI: 3.30-6.82%) and urban dwellers (OR = 2.69; 95% CI: 2.11-3.44%) were associated factors with male involvement in PMTCT.
Conclusions:
The level of male involvement in PMTCT of HIV in Ethiopia is low. Male involvement is influenced by knowledge on HIV and urban residence. The government of Ethiopia should give concern for rural male population to enhance their involvement in the prevention of mother-to-child HIV transmission.
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