REVIEW PAPER
Investigating the needs and barriers
for prevention, control, and treatment of HIV/AIDS in transgender population: a systematic review of literature
More details
Hide details
1
Department of Urology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
2
Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
3
Students Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
4
Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.
5
Student Research Committee, Kurdistan University of Medical Sciences Sanandaj, Iran.
Submission date: 2022-03-26
Final revision date: 2022-04-13
Acceptance date: 2022-04-18
Online publication date: 2024-09-20
Corresponding author
Yousef Moradi
Social Determinants of Health Research Center, Research Institute
for Health Development, Kurdistan University of Medical Sciences,
Sanandaj 1598976513, Iran, phone: +98-9183847065,
fax: +98-873323000, e-mail: Yousefmoradi211@yahoo.com
HIV & AIDS Review 2024;23(3):198-203
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The purpose of this systematic review was to identify the health needs related to prevention, control, and treatment of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) in transgender people from the perspective of transgender individuals and health policy-makers.
Material and Methods:
Original studies (case-control, cohort, cross-sectional), interventional studies, clinical trials, and qualitative studies were included in the review. All international electronic databases, such as PubMed (Medline), Scopus, Web of Sciences, Cochrane, PsycINFO, and Google Scholar (gray literature) were searched from December 1990 to December 2019. Quality of articles was assessed using STROBE (strengthening the reporting of observational studies in epidemiology), CONSORT (consolidated standards of reporting trials), and SRQR (standards for reporting qualitative research) checklists. Search strategy, data extraction, and quality evaluation of papers were performed by two researchers independently.
Results:
The results showed that from the perspective of health policy-makers, the needs related to control, prevention, and treatment of HIV/AIDS in transgender population were the need for optimal access to AIDS-related services, such as easy access to diagnostic tests, and the need to increase insufficient awareness of the ways of transmission of the disease and its symptoms. From the perspective of transgender people, the need for more care and attention after surgery, such as access to appropriate therapeutic hormones and disposable syringes, were more important.
Conclusions:
According to the results, health policy-makers can develop an appropriate plan for timely access to HIV/AIDS control, prevention, and treatment services for transgender individuals. The drawback of this systematic review is limited access to the full texts of some of the original articles. Moreover, many articles reported brief results only.
REFERENCES (40)
1.
Di Ceglie D. Gender identity disorder in young people. Adv Psychiatr Treat 2000; 6: 458-466.
2.
Gul S. Liberate Me! my soul trapped in a wrong body. Optmial medical care for gender identity disorder. Pharm Innov 2013; 2: 1-7.
3.
Patrick R, Jain J, Harvey-Vera A, Semple SJ, Rangel G, Patterson TL,et al. Perceived barriers to pre-exposure prophylaxis use among HIV-negative men who have sex with men in Tijuana, Mexico: a latent class analysis. PLoS One 2019; 14: e0221558. DOI: 10.1371/journal.pone.0221558.
4.
Rosen JG, Malik M, Cooney EE, Wirtz AL, Yamanis T, Lujan M, et al. Antiretroviral treatment interruptions among Black and Latina transgender women living with HIV: characterizing co-occurring, multilevel factors using the gender affirmation framework. AIDS Behav 2019; 23: 2588-2599.
5.
Baral SD, Poteat T, Strömdahl S, Wirtz AL, Guadamuz TE, Beyrer C. Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. Lancet Infect Dis 2013; 13: 214-222.
6.
Lindley LL, Nicholson TJ, Kerby MB, Lu N. HIV/STI associated risk behaviors among self-identified lesbian, gay, bisexual, and transgender college students in the United States. AIDS Educ Prev 2003; 15: 413-429.
7.
Evans MG, Cloete A, Zungu N, Simbayi LC. HIV risk among men who have sex with men, women who have sex with women, lesbian, gay, bisexual and transgender populations in South Africa: a mini- review. Open AIDS J 2016; 10: 49-64.
8.
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta analyses: the PRISMA statement. Ann Intern Med 2009; 151: 264-269.
9.
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. Open Med 2009; 3: e123-e130.
10.
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med 2007; 147: 573-577.
11.
Moher D, Schulz KF, Altman D; CONSORT Group (Consolidated Standards of Reporting Trials). The CONSORT statement: revised recommendations for improving the quality of reports of parallel- group randomized trials. JAMA 2001; 285: 1987-1991.
12.
O’Brien BC, Harris IB, Beckman TJ, Reed DA, Cook DA. Standards for reporting qualitative research: a synthesisof recommendations. Acad Med 2014; 89: 1245-1251.
13.
Edwards JW, Fisher DG, Reynolds GL. Male-to-female transgender and transsexual clients of HIV service programs in Los Angeles County, California. Am J Public Health 2007; 97: 1030-1033.
14.
Bauer GR, Hammond R, Travers R, Kaay M, Hohenadel KM, Boyce M.“I don’t think this is theoretical; this is our lives”: how erasure impacts health care for transgender people. J Assoc Nurses AIDS Care 2009; 20: 348-361.
15.
Garofalo R, Johnson AK, Kuhns LM, Cotten C, Joseph H, Margolis A. Life skills: evaluation of a theory-driven behavioral HIV prevention intervention for young transgender women. J Urban Health 2012; 89: 419-431.
16.
Boyce S, Barrington C, Bolaños H, Arandi CG, Paz-Bailey G. Facilitating access to sexual health services for men who have sex with men and male-to-female transgender persons in Guatemala City. Cult Health Sex 2012; 14: 313-327.
17.
Beattie TS, Bhattacharjee P, Suresh M, Isac S, Ramesh BM, Moses S. Personal, interpersonal and structural challenges to accessing HIV testing, treatment and care services among female sex workers, men who have sex with men and transgenders in Karnataka state, South India. J Epidemiol Community Health 2012; 66 Suppl 2: ii42-48. DOI: 10.1136/jech-2011-200475.
18.
Coyne CA, Yuodsnukis BT, Chen D. Gender dysphoria: optimizing healthcare for transgender and gender diverse youth with a multidisciplinary approach. Neuropsychiatr Dis Treat 2023; 19: 479-493. .
19.
Johnson M, Afonina L, Haanyama O. The challenges of testing for HIV in women: experience from the UK and other European countries. Antivir Ther 2013; 18 Suppl 2: 19-25. DOI: 10.3851/IMP2637.
20.
Levy ME, Wilton L, Phillips G 2nd, Glick SN, Kuo I, Brewer RA, et al. Understanding structural barriers to accessing HIV testing and prevention services among black men who have sex with men (BMSM) in the United States. AIDS Behav 2014; 18: 972 996.
21.
Bouris A, Voisin D, Pilloton M, Flatt N, Eavou R, Hampton K, et al. Project nGage: network supported HIV care engagement for younger black men who have sex with men and transgender persons. J AIDS Clin Res 2013; 4: 10.4172/2155-6113.1000236. DOI: 10.4172/2155-6113.1000236.
22.
Goswami P, Rachakulla HK, Ramakrishnan L, Mathew S, Ramanathan S, George B, et al. An assessment of a large-scale HIV prevention programme for high-risk men who have sex with men and transgenders in Andhra Pradesh, India: using data from routine programme monitoring and repeated cross-sectional surveys. BMJ Open 2013; 3: e002183. DOI: 10.1136/bmjopen-2012-002183.
23.
Andrasik MP, Yoon R, Mooney J, Broder G, Bolton M, Votto T, et al. Exploring barriers and facilitators to participation of male-to female transgender persons in preventive HIV vaccine clinical trials. Prev Sci 2014; 15: 268-276.
24.
Daniels J, Lane T, Struthers H, Maleke K, Moges W, McIntyre J, et al. Assessing the feasibility of smartphone apps for HIV-care research with MSM and transgender individuals in Mpumalanga, South Africa. J Int Assoc Provid AIDS Care 2017; 16: 433-439.
25.
Logie CH, Lys CL, Dias L, Schott N, Zouboules MR, MacNeill N, et al. “Automatic assumption of your gender, sexuality and sexual practices is also discrimination”: exploring sexual healthcare experiences and recommendations among sexually and gender diverse persons in Arctic Canada. Health Soc Care Community 2019; 27: 1204-1213. .
26.
Melendez RM, Exner TA, Ehrhardt AA, Dodge B, Remien RH, Rotheram-Borus MJ, et al. Health and health care among male-to female transgender persons who are HIV positive. Am J Public Health 2006; 96: 1034-1037. .
27.
Siskind RL, Andrasik M, Karuna ST, Broder GB, Collins C, Liu A, et al. Engaging transgender people in NIH-funded HIV/AIDS clinical trials research. J Acquir Immune Defic Syndr 2016; 72 Suppl 3 (Suppl 3): S243-247. DOI: 10.1097/QAI.0000000000001085.
28.
Newman PA, Lee SJ, Roungprakhon S, Tepjan S. Demographic and behavioral correlates of HIV risk among men and transgender women recruited from gay entertainment venues and community- based organizations in Thailand: implications for HIV prevention. Prev Sci 2012; 13: 483-492.
29.
Reisner SL, Bailey Z, Sevelius J. Racial/ethnic disparities in history of incarceration, experiences of victimization, and associated health indicators among transgender women in the U.S. Women Health 2014; 54: 750-767. .
30.
Poteat T, Wirtz AL, Reisner S. Strategies for engaging transgender populations in HIV prevention and care. Curr Opin HIV AIDS 2019; 14: 393-400. .
31.
Ragonnet-Cronin M, Hodcroft EB, Wertheim JO. Understanding disclosed and cryptic HIV transmission risk via genetic analysis: what are we missing and when does it matter? Curr Opin HIV AIDS 2019; 14: 205-212. .
32.
Ragonnet-Cronin M, Hu YW, Morris SR, Sheng Z, Poortinga K, Wertheim JO. HIV transmission networks among transgender women in Los Angeles County, CA, USA: a phylogenetic analysis of surveillance data. Lancet HIV 2019; 6: e164-e172. DOI: 10.1016/S2352-3018(18)30359-X.
33.
Ganju D, Saggurti N. Stigma, violence and HIV vulnerability among transgender persons in sex work in Maharashtra, India. Cult Health Sex 2017; 19: 903-917.
34.
Winter S, Diamond M, Green J, Karasic D, Reed T, Whittle S, et al. Transgender people: health at the margins of society. Lancet 2016; 388: 390-400.
35.
de Mendoza C. UNAIDS Update Global HIV Numbers. AIDS Rev 2019; 21: 170-171.
36.
Del Rio C. Editorial: can we end HIV as a public health problem globally? Progress towards achieving the UNAIDS 90-90-90 goals. Curr Opin HIV AIDS 2019; 14: 439-441.
37.
Phillips JC, Patsdaughter CA. Toward a healthier tomorrow: competent health and HIV care for transgender persons. J Assoc Nurses AIDS Care 2010; 21: 183-185. .
38.
Aguayo-Romero RA, Reisen CA, Zea MC, Bianchi FT, Poppen PJ. Gender affirmation and body modification among transgender persons in Bogotá, Colombia. Int J Transgend 2015; 16: 103-115.
39.
Nemoto T, Operario D, Keatley J, Han L, Soma T. HIV risk behaviors among male-to-female transgender persons of color in San Francisco. Am J Public Health 2004; 94: 1193-1199.
40.
Wolf RC, Adams D, Dayton R, Verster A, Wong J, Romero M, et al. Putting the t in tools: a roadmap for implementation of new global and regional transgender guidance. J Int AIDS Soc 2016; 19 (3 Suppl 2): 20801. DOI: 10.7448/IAS.19.3.20801.