A study on local therapy technique that can be used in treatment of AIDS and some other diseases
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Gizan General Hospital, KSA, Saudi Arabia
Submission date: 2019-03-08
Final revision date: 2019-05-06
Acceptance date: 2019-05-07
Publication date: 2019-06-17
HIV & AIDS Review 2019;18(3):193-198
Local therapy is treatment that is directed to a specific organ or limited area of the body. It can shorten the length of infection, reduce complications, and reduce the spread to other tissues or organs. In some cases, it may be more effective, more specific and better than systematic therapy, with fewer side effects. In this research, I tried to evaluate and develop the use and implementation of some of these local therapy medications in treatment of some diseases including acquired immunodeficiency syndrome (AIDS).

Material and methods:
I used in this research direct face-to-face questionnaires to get my answers and data from adult people who experienced these diseases and therapies before. They provided me with all required information without identification data and without the need of any consent or legal permissions. Also I collected retrospectively registered data as nominal data to be easier in calculation and evaluation with a probability value p < 0.05.

I got some data and results with a significant difference, e.g. 103 (103 from 129 total sample = 79.84%) patients with minor superficial wounds, who have an experience with these diseases and both of local and systematic therapies before, said that they had a faster recovery (by 2-3 days) if using a combination of a systematic antibiotic with a local antibiotic cream than using the same systematic antibiotic alone. Also, 4 patients (from a total sample of 6 = 66.66%) with AIDS got a faster and better outcome in decreasing viral load if using a combination of systematic oral antiretroviral treatment with injectable intramuscular injection of antiretroviral treatment (oral zidovudine 300 mg + lamivudine 150 mg USP, one tablet once daily for 24 weeks and with injection (intramuscular dosing) antiretroviral therapy, as injectable cabotegravir 400 mg + rilpivirine 600 mg one vial dose every 4 weeks for 24 weeks).

The study revealed that we can use and develop some medications as an effective therapy in treatment of some diseases, including human immunodeficiency virus. I have suggested in this research a new additional way for treatment of AIDS, taking into account the possible side effects.

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