RESEARCH PAPER
Health-related quality of life of HIV patients with and without tuberculosis registered in a Tertiary Hospital in Port Harcourt, Nigeria
 
More details
Hide details
 
Submission date: 2017-08-17
 
 
Final revision date: 2018-03-01
 
 
Acceptance date: 2018-03-02
 
 
Publication date: 2018-09-25
 
 
HIV & AIDS Review 2018;17(3):210-217
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Little is known about health-related quality of life (HRQOL) of patients who suffer from human immunodeficiency virus (HIV)/tuberculosis (TB) in Nigeria. This study was carried out to measure and compare the HRQOL of HIV patients with and without TB at the HIV Clinic of University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.

Material and methods:
A comparative cross-sectional study design and simple random sampling was used to recruit 144 HIV patients with TB and 144 HIV patients without TB. Information were collected on socio-demographic and socioeconomic variables, while their HRQOL was measured using the 26-item World Health Organization Quality of Life instrument. Univariate and bivariate analysis was carried out in Epi-info 7.

Results:
Females constituted 52% and 56% of HIV-only and HIV/TB co-infected groups, respectively. Their mean ages were 36.03 ± 10.92 and 35.69 ± 10.28 years, respectively (p = 0.532). HRQOL score ranged from 61.9 to 78.5 for HIV patients, and 61.6 to 75.8 for the co-infected patients. Co-infected patients had lower HRQOL in the physical (p = 0.016), psychological (p = 0.006), and global (p = 0.029) domains of HRQOL than HIV-only patients. The two groups did not differ significantly in the social and environmental domains (p > 0.05).

Conclusions:
The co-morbidity condition of HIV/TB significantly lowers the quality of life of sufferers. Attention should be focused on the medical and psychological management of HIV/TB co-infected patients in order to enhance their QOL.

 
REFERENCES (34)
1.
Joint United Nations Programme on HIV/AIDS (UNAIDS). Report on the global AIDS epidemic. UNAIDS, Geneva 2013.
 
2.
Joint United Nations Programme on HIV/AIDS (UNAIDS). Global AIDS Epidemic. Facts and Figures. UNAIDS, Geneva 2012.
 
3.
Joint United Nations Programme on HIV/AIDS (UNAIDS). Annual Report: towards universal access. UNAIDS, Geneva 2008.
 
4.
National Agency for the Control of HIV/AIDS (NACA). Annual Progress Report: Update on the HIV/AIDS Epidemic and Response in Nigeria. NACA, Abuja 2011.
 
5.
Joint United Nations Programme on HIV/AIDS (UNAIDS). Report on the global AIDS epidemic. UNAIDS, Geneva 2008.
 
6.
World Health Organization (WHO). Treatment of Tuberculosis guidelines for national programmes – 3rd Edition. WHO, Geneva 2003.
 
7.
World Health Organization (WHO). Global Tuberculosis Control. WHO, Geneva 2011.
 
8.
World Health Organization (WHO). Measuring Quality of Life: Division of Mental Health and Prevention of Substance Abuse. WHO, Geneva 1997.
 
9.
Mbada CE, Onayemi O, Ogunmoyole Y, et al. Health-related quality of life and physical functioning in people living with HIV/AIDS: a case-control design. Health Qual Life Outcomes 2013; 11: 106.
 
10.
Aggarwal AN. Health-related quality of life: A neglected aspect of pulmonary tuberculosis. Lung India 2010; 27: 1-3.
 
11.
Phillips D. Quality of Life: Concept, Policy and Practice. 1st ed. Routledge, London 2006.
 
12.
Porter K, Babiker A, Bhaskaran K. Determinants of survival following HIV-1 seroconversion after the introduction of HAART. Lancet 2003; 362: 1267-1274.
 
13.
Wig N, Lekshmi R, Pal H, et al. The impact of HIV/AIDS on the quality of life: a cross sectional study in North India. Indian J Med Sci 2006; 60 (Suppl 1): 3-12.
 
14.
Tiwari MK, Verma S, Agrawal D, Agrawal H. Quality of life of patients with HIV infection. Indian J Soc Sci Res 2009; 6: 8.
 
15.
Folasire OF, Irabor AE, Folasire AM. Quality of life of People living with HIV and AIDS attending the Antiretroviral Clinic, University College Hospital, Nigeria. African J Prim Heal Care Fam Med 2012; 4 (Suppl 1): 8.
 
16.
Federal Ministry of Health (FMOH). National HIV/AIDS and Reproductive Health Survey. FMOH, Abuja 2014.
 
17.
Deribew A, Tesfaye M, Hailmichael Y, et al. Tuberculosis and HIV co-infection: its impact on quality of life. Health Qual Life Outcomes 2009; 7: 105.
 
18.
World Health Organization (WHO). The World Health Organization Quality of Life (WHOQOL-BREF). WHO, Geneva 2004.
 
19.
World Health Organization (WHO). Programme on Mental Health: WHOQOL User Manual. WHO, Geneva 1998.
 
20.
Saxena S, Carlson D, Billington R. The WHO quality of life assessment instrument (WHOQOL-Bref): the importance of its items for cross-cultural research. Qual Life Res 2001; 10 (Suppl 8): 711-721.
 
21.
Akinpelu AO, Maruf FA, Adegoke BO. Validation of a Yoruba translation of the World Health Organization’s quality of life scale-short form among stroke survivors in Southwest Nigeria. Afr J Med Med Sci 2006; 35 (S4): 417-424.
 
22.
Odole AC, Akinpelu AO. Validity and internal consistency of a Hausa version of the Ibadan Knee/Hip Osteoarthritis Outcome Measure. Health Qual Life Outcomes 2008; 6 (Suppl 1): 86.
 
23.
Fatiregun A, Mofolorunsho K, Osagbemi K. Quality of Life of People Living With HIV/AIDS in Kogi State, Nigeria. Benin J Postgrad Med 2009; 11 (Suppl 1): 21-25.
 
24.
Bello SI, Bello IK. Quality of life of HIV/AIDS patients in a secondary health care facility, Ilorin, Nigeria. Proc (Bayl Univ Med Cent) 2013; 26 (Suppl 2): 116-119.
 
25.
Akinboro AO, Akinyemi SO, Olaitan PB, et al. Quality of life of Nigerians living with human immunodeficiency virus. Pan Afr Med J 2014; 18: 234.
 
26.
Osei-Yeboah J, Owiredu W, Norgbe GK. Quality of Life of People Living with HIV/AIDS in the Ho Municipality, Ghana: A Cross-Sectional Study. AIDS Res Treat 2017; 2017: 6806951.
 
27.
Giri S, Neupane M, Pant S, et al. Quality of life among people living with acquired immune deficiency syndrome receiving antiretroviral therapy: a study from Nepal. HIV AIDS Res Palliat Care 2013; 5: 277-282.
 
28.
Odimegwu C, Akinyemi J, Alabi O. HIV-Stigma in Nigeria: Review of Research Studies, Policies, and Programmes. AIDS Res Treat 2017; 2017: 5812650.
 
29.
Tesfay A, Gebremariam A, Gerbaba M, Abrha H. Gender differences in health-related quality of life among people living with HIV on highly active antiretroviral therapy in Mekelle town, northern Ethiopia. Biomed Res Int 2015; 2015: 516369.
 
30.
Santos E, Morandi dos C, França I, Lopes F. Quality of life of people living with HIV/AIDS in São Paulo Brazil. Revista de Saude Publica 2007; 41 (Suppl 2): 64-71.
 
31.
Egbe CO, Dakum PS, Ekong E, et al. Depression, suicidality, and alcohol use disorder among people living with HIV/AIDS in Nigeria. BMC Public Health 2017; 17: 542.
 
32.
Wakawa I, Said J, Abba W, et al. The Impact of Comorbid Clinical Depression on the Health-Related Quality of Life of Adults on Highly Active Antiretroviral Therapy in Maiduguri, Northeastern Nigeria. Indian J Psychol Med 2014; 36 (Suppl 4): 408-417.
 
33.
Akpa OM, Bamgboye EA. Correlates of the Quality of life of Adolescents in families affected by HIV/AIDS in Benue State, Nigeria. Vulnerable Child Youth Stud 2015; 10 (Suppl 3): 225-242.
 
34.
Idler EL, Benyamini Y. Self-rated health and mortality: a review of twenty-seven community studies. J Health Soc Behav 1997; 38: 21-37.
 
eISSN:1732-2707
ISSN:1730-1270
Journals System - logo
Scroll to top