CASE REPORT
Colitis as a clinical manifestation
of disseminated histoplasmosis in HIV-positive patient: a case report
1
Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, RSUP Prof. dr. I.G.N.G Ngoerah General Hospital,
Bali, Indonesia
2
Department of Tropical Infections, Faculty of Medicine, Universitas Udayana, RSUP Prof. dr. I.G.N.G Ngoerah General Hospital,
Bali, Indonesia
3
Department of Anatomical Pathology, Faculty of Medicine, Universitas Udayana, RSUP Prof. dr. I.G.N.G Ngoerah General
Hospital, Bali, Indonesia
Submission date: 2023-07-23
Final revision date: 2023-12-06
Acceptance date: 2023-12-20
Online publication date: 2025-03-16
Corresponding author
Daniel Zaputra
Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, RSUP Prof. dr. I.G.N.G Ngoerah General Hospital, Bali, Indonesia
Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, RSUP Prof. dr. I.G.N.G Ngoerah General Hospital, Bali, Indonesia
HIV & AIDS Review 2025;24(1):79-82
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Disseminated histoplasmosis is a systemic fungal infection resulting from co-infection in severely immunosuppressed patients, such as those with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome.
Case report:
In this case report, a 49-year-old female HIV-positive patient, with complaints of black stool with fresh blood since two months was presented. Hemorrhoidectomy, followed by colonoscopy and biopsy were performed, confirming histoplasmosis infection diagnosis.
Conclusions:
The spectrum of clinical manifestations of disseminated histoplasmosis in HIV-infected patients are non-specific. Most disseminated histoplasmosis patients suffer from gastrointestinal problems. Anti-fungal therapy in histoplasmosis shows a good clinical response.
Disseminated histoplasmosis is a systemic fungal infection resulting from co-infection in severely immunosuppressed patients, such as those with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome.
Case report:
In this case report, a 49-year-old female HIV-positive patient, with complaints of black stool with fresh blood since two months was presented. Hemorrhoidectomy, followed by colonoscopy and biopsy were performed, confirming histoplasmosis infection diagnosis.
Conclusions:
The spectrum of clinical manifestations of disseminated histoplasmosis in HIV-infected patients are non-specific. Most disseminated histoplasmosis patients suffer from gastrointestinal problems. Anti-fungal therapy in histoplasmosis shows a good clinical response.
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