RESEARCH PAPER
Serum levels of vitamin D, magnesium, calcium, iron, and total iron binding capacity in HIV-infected patients
Masoud Sadeghi
4,5
1
Department of Infectious Diseases and Tropical Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
2
Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
3
Department of Oral and Maxillofacial Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
4
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
5
Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
Submission date: 2018-08-08
Acceptance date: 2018-09-14
Publication date: 2019-03-10
HIV & AIDS Review 2019;18(2):148-152
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Alterations of vitamins and minerals have been seen in patients with the human immune virus (HIV) in numerous studies. This study aimed to evaluate serum levels of vitamin D, magnesium, calcium, iron, and total iron binding capacity (TIBC) in HIV-infected patients compared with controls in western Iran.
Material and methods:
Ninety-eight HIV-infected prisoners and 98 healthy controls were selected for the study in 2016. Cluster of differentiation 4 (CD4) was checked in all HIV-infected patients. Age, sex, vitamin D, calcium, magnesium, iron, and TIBC were checked for each person in both groups.
Results:
The mean age (range) of the HIV-infected and the healthy control groups was 40.11 years (21-68 years) and 45.59 (18-85 years), respectively. Vitamin D, calcium, iron and TIBC levels were significantly different in the two groups. There was a significant correlation between calcium and iron levels and the CD4 count.
Conclusions:
There were significant differences in vitamin D, calcium, iron, and TIBC levels in the HIV-infected patients compared to the healthy controls. Therefore, the results show the correlation between these levels and the incidence of HIV. In addition, the significant difference between calcium and iron levels with the CD4 counts can enhance the correlation.
Alterations of vitamins and minerals have been seen in patients with the human immune virus (HIV) in numerous studies. This study aimed to evaluate serum levels of vitamin D, magnesium, calcium, iron, and total iron binding capacity (TIBC) in HIV-infected patients compared with controls in western Iran.
Material and methods:
Ninety-eight HIV-infected prisoners and 98 healthy controls were selected for the study in 2016. Cluster of differentiation 4 (CD4) was checked in all HIV-infected patients. Age, sex, vitamin D, calcium, magnesium, iron, and TIBC were checked for each person in both groups.
Results:
The mean age (range) of the HIV-infected and the healthy control groups was 40.11 years (21-68 years) and 45.59 (18-85 years), respectively. Vitamin D, calcium, iron and TIBC levels were significantly different in the two groups. There was a significant correlation between calcium and iron levels and the CD4 count.
Conclusions:
There were significant differences in vitamin D, calcium, iron, and TIBC levels in the HIV-infected patients compared to the healthy controls. Therefore, the results show the correlation between these levels and the incidence of HIV. In addition, the significant difference between calcium and iron levels with the CD4 counts can enhance the correlation.
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